Innovation research within the Business Intelligence Innovation Hub is addressing the challenge to make the (regional) business and innovation ecosystem more innovative and competitive. Of special interest are small- and medium sized companies by maximizing their innovation potential. One central role is the extensive linkage of actors within business and innovation ecosystems through establishment of quadruple helix clusters/networks and the development and implementation of new participatory methods and tools to engage the stakeholders – managers and decision makers – in innovation processes. Innovation research within the Business Intelligence Innovation Hub focus on urban innovation ecosystems for companies, innovation in public procurement and smart government ecosystems as well as technological innovation for small- and medium sized companies.